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Usefulness of Faecal Calprotectin Measurement in Children with Various Types of Inflammatory Bowel Disease
Joint Authors
Komraus, Marzena
Wos, Halina
Grzybowska-Chlebowczyk, Urszula
Grzybowska-Chlebowczyk, Urszula
Więcek, Sabina
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
The aim of the study was to assess the usefulness of the FC measurement in children with various types of IBD and relation to the disease activity.
Patients and Methods.
91 patients (49 boys: 53.85% and 42 girls: 46.15%, mean age: 13.38 years, range 6–18 years) were included in the analysis.
Patients were divided into the groups: B1—24 children with CD, B2—16 patients with UC, and a group comprising 31 children with other types of colitis; the control group (K) comprised 20 healthy children.
FC was assayed by ELISA method, using Phical test (Calpro).
Results.
The mean faecal calprotectin concentrations were higher in children with CD and UC as compared to healthy controls, patients with eosinophilic, lymphocytic, and nonspecific colitis.
A positive correlation was observed between FC concentrations and the disease activity (the PCDAI scale, the Truelove-Witts Scale, and the endoscopic Rachmilewitz Index).
Conclusion.
It seems that the FC concentrations can be a useful, safe, and noninvasive test in children suspected for IBD, since FC concentration is higher in children with CD and UC than in patients with other inflammatory diseases.
American Psychological Association (APA)
Komraus, Marzena& Wos, Halina& Więcek, Sabina& Grzybowska-Chlebowczyk, Urszula& Grzybowska-Chlebowczyk, Urszula. 2012. Usefulness of Faecal Calprotectin Measurement in Children with Various Types of Inflammatory Bowel Disease. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-1029423
Modern Language Association (MLA)
Komraus, Marzena…[et al.]. Usefulness of Faecal Calprotectin Measurement in Children with Various Types of Inflammatory Bowel Disease. Mediators of Inflammation No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-1029423
American Medical Association (AMA)
Komraus, Marzena& Wos, Halina& Więcek, Sabina& Grzybowska-Chlebowczyk, Urszula& Grzybowska-Chlebowczyk, Urszula. Usefulness of Faecal Calprotectin Measurement in Children with Various Types of Inflammatory Bowel Disease. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-1029423
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029423