Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge
Joint Authors
Mommsen, Philipp
Flohé, Sascha
van Griensven, Martijn
Hildebrand, Frank
Frink, Michael
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-13
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Numerous multiple trauma and surgical patients suffer from accidental hypothermia.
While induced hypothermia is commonly used in elective cardiac surgery due to its protective effects, accidental hypothermia is associated with increased posttraumatic complications and even mortality in severely injured patients.
This paper focuses on protective molecular mechanisms of hypothermia on apoptosis and the posttraumatic immune response.
Although information regarding severe trauma is limited, there is evidence that induced hypothermia may have beneficial effects on the posttraumatic immune response as well as apoptosis in animal studies and certain clinical situations.
However, more profound knowledge of mechanisms is necessary before randomized clinical trials in trauma patients can be initiated.
American Psychological Association (APA)
Frink, Michael& Flohé, Sascha& van Griensven, Martijn& Mommsen, Philipp& Hildebrand, Frank. 2012. Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1029438
Modern Language Association (MLA)
Frink, Michael…[et al.]. Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge. Mediators of Inflammation No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-1029438
American Medical Association (AMA)
Frink, Michael& Flohé, Sascha& van Griensven, Martijn& Mommsen, Philipp& Hildebrand, Frank. Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1029438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029438