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Infertility and Adenomyosis
Joint Authors
Campo, Sebastiano
Campo, Vincenzo
Benagiano, Giuseppe
Source
Obstetrics and Gynecology International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Classically, the diagnosis of adenomyosis has only been possible on a hysterectomy specimen, usually in women in their late fourth and fifth decades, and, therefore, evaluating any relationship with infertility was simply not possible.
As a consequence, to this day, no epidemiologic data exists linking adenomyosis to a state of subfertility.
Today, new imaging techniques have enabled a noninvasive diagnosis at a much earlier time and a number of single-case or small series reports have appeared showing that medical, surgical, or combined treatment can restore fertility in women with adenomyosis, an indirect proof of an association.
At the functional level, several anomalies found in the so-called junctional zone, or inner myometrium, in adenomyosis patients have been shown to be associated with poor reproductive performance, mainly through perturbed uterine peristalsis.
Additional evidence for an association comes from experimental data: in baboons, adenomyosis is associated with lifelong primary infertility, as well as to endometriosis.
Finally, indirect proof comes from studies of the eutopic and ectopic endometrium in women with adenomyosis proving the existence of an altered endometrial function and receptivity.
In conclusion, sufficient indirect proof exists linking adenomyosis to infertility to warrant systematic clinical studies.
American Psychological Association (APA)
Campo, Sebastiano& Campo, Vincenzo& Benagiano, Giuseppe. 2011. Infertility and Adenomyosis. Obstetrics and Gynecology International،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1029970
Modern Language Association (MLA)
Campo, Sebastiano…[et al.]. Infertility and Adenomyosis. Obstetrics and Gynecology International No. 2012 (Dec. 2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1029970
American Medical Association (AMA)
Campo, Sebastiano& Campo, Vincenzo& Benagiano, Giuseppe. Infertility and Adenomyosis. Obstetrics and Gynecology International. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1029970
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029970