Optimization of Parameters for a More Efficient Use ofAdipose-Derived Stem Cells in Regenerative Medicine Therapies
Joint Authors
Aguena, Meire
Dalto Fanganiello, Roberto
Tissiani, Luiz Alexandre Lorico
Ishiy, Felipe Augusto André
Atique, Rodrigo
Passos-Bueno, Maria Rita
Alonso, Nivaldo
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-14
Country of Publication
Egypt
No. of Pages
7
Abstract EN
Adipose tissue-derived stem cells (ASCs) association to fat in autologous lipotransfer is promising for a more effective soft tissue reconstruction, and optimization of protocols to isolate ASCs from lipoaspirate fat is much needed.
We demonstrated that an increase in adipocyte differentiation is dependent on the number of ASCs.
In a sample of 10 donors, we found a higher concentration of nucleated cells in the lower abdomen compared to flank (P=0.015).
In a sample of 6 donors we did not find differences in the cell yield obtained by manual or pump-assisted aspiration (P=0.56).
We suggest that the increase in the number of ASCs in the reinjected fat may enhance the efficiency of newly formed adipose tissue and that the anatomical region from which to harvest fat tissue needs to be considered to optimize the number of ASCs in the harvested tissue.
Finally, pump-assisted aspiration can be used without any significant harm to the viability of cells.
American Psychological Association (APA)
Aguena, Meire& Dalto Fanganiello, Roberto& Tissiani, Luiz Alexandre Lorico& Ishiy, Felipe Augusto André& Atique, Rodrigo& Alonso, Nivaldo…[et al.]. 2012. Optimization of Parameters for a More Efficient Use ofAdipose-Derived Stem Cells in Regenerative Medicine Therapies. Stem Cells International،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1030007
Modern Language Association (MLA)
Aguena, Meire…[et al.]. Optimization of Parameters for a More Efficient Use ofAdipose-Derived Stem Cells in Regenerative Medicine Therapies. Stem Cells International No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1030007
American Medical Association (AMA)
Aguena, Meire& Dalto Fanganiello, Roberto& Tissiani, Luiz Alexandre Lorico& Ishiy, Felipe Augusto André& Atique, Rodrigo& Alonso, Nivaldo…[et al.]. Optimization of Parameters for a More Efficient Use ofAdipose-Derived Stem Cells in Regenerative Medicine Therapies. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1030007
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030007