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Prospective In Vitro Models of Channelopathies and Cardiomyopathies
Joint Authors
Kawaguchi, Nanako
Nakanishi, Toshio
Hayama, Emiko
Furutani, Yoshiyuki
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-30
Country of Publication
Egypt
No. of Pages
10
Abstract EN
An in vitro heart disease model is a promising model used for identifying the genes responsible for the disease, evaluating the effects of drugs, and regenerative medicine.
We were interested in disease models using a patient-induced pluripotent stem (iPS) cell-derived cardiomyocytes because of their similarity to a patient’s tissues.
However, as these studies have just begun, we would like to review the literature in this and other related fields and discuss the path for future models of molecular biology that can help to diagnose and cure diseases, and its involvement in regenerative medicine.
The heterogeneity of iPS cells and/or differentiated cardiomyocytes has been recognized as a problem.
An in vitro heart disease model should be evaluated using molecular biological analyses, such as mRNA and micro-RNA expression profiles and proteomic analysis.
American Psychological Association (APA)
Kawaguchi, Nanako& Hayama, Emiko& Furutani, Yoshiyuki& Nakanishi, Toshio. 2012. Prospective In Vitro Models of Channelopathies and Cardiomyopathies. Stem Cells International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1030021
Modern Language Association (MLA)
Kawaguchi, Nanako…[et al.]. Prospective In Vitro Models of Channelopathies and Cardiomyopathies. Stem Cells International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-1030021
American Medical Association (AMA)
Kawaguchi, Nanako& Hayama, Emiko& Furutani, Yoshiyuki& Nakanishi, Toshio. Prospective In Vitro Models of Channelopathies and Cardiomyopathies. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1030021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030021