Growth Factors and Anticatabolic Substances for Prevention and Management of Intervertebral Disc Degeneration
Joint Authors
Longo, Umile Giuseppe
Petrillo, Stefano
Franceschetti, Edoardo
Denaro, Vincenzo
Maffulli, Nicola
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-21
Country of Publication
Egypt
No. of Pages
12
Abstract EN
Intervertebral disc (IVD) degeneration is frequent, appearing from the second decade of life and progressing with age.
Conservative management often fails, and patients with IVD degeneration may need surgical intervention.
Several treatment strategies have been proposed, although only surgical discectomy and arthrodesis have been proved to be predictably effective.
Biological strategies aim to prevent and manage IVD degeneration, improving the function and anabolic and reparative capabilities of the nucleus pulposus and annulus fibrosus cells and inhibiting matrix degradation.
At present, clinical applications are still in their infancy.
Further studies are required to clarify the role of growth factors and anticatabolic substances for prevention and management of intervertebral disc degeneration.
American Psychological Association (APA)
Longo, Umile Giuseppe& Petrillo, Stefano& Franceschetti, Edoardo& Maffulli, Nicola& Denaro, Vincenzo. 2011. Growth Factors and Anticatabolic Substances for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1030046
Modern Language Association (MLA)
Petrillo, Stefano…[et al.]. Growth Factors and Anticatabolic Substances for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1030046
American Medical Association (AMA)
Longo, Umile Giuseppe& Petrillo, Stefano& Franceschetti, Edoardo& Maffulli, Nicola& Denaro, Vincenzo. Growth Factors and Anticatabolic Substances for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1030046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030046