Mesenchymal Stem Cell for Prevention and Management of Intervertebral Disc Degeneration
Joint Authors
Longo, Umile Giuseppe
Petrillo, Stefano
Franceschetti, Edoardo
Denaro, Vincenzo
Papapietro, Nicola
Maffulli, Nicola
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-04
Country of Publication
Egypt
No. of Pages
7
Abstract EN
Intervertebral disc degeneration (IVD) is a frequent pathological condition.
Conservative management often fails, and patients with IVD degeneration may require surgical intervention.
Several treatment strategies have been proposed, although only surgical discectomy and arthrodesis have been proved to be predictably effective.
The aim of biological strategies is to prevent and manage IVD degeneration, improve the function, the anabolic and reparative capabilities of the nucleus pulposus and annulus fibrosus cells, and inhibit matrix degradation.
At present, clinical applications are still in their infancy.
Further studies are required to clarify the role of mesenchymal stem cells and gene therapy for the prevention and treatment of IVD degeneration.
American Psychological Association (APA)
Longo, Umile Giuseppe& Papapietro, Nicola& Petrillo, Stefano& Franceschetti, Edoardo& Maffulli, Nicola& Denaro, Vincenzo. 2012. Mesenchymal Stem Cell for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1030051
Modern Language Association (MLA)
Longo, Umile Giuseppe…[et al.]. Mesenchymal Stem Cell for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1030051
American Medical Association (AMA)
Longo, Umile Giuseppe& Papapietro, Nicola& Petrillo, Stefano& Franceschetti, Edoardo& Maffulli, Nicola& Denaro, Vincenzo. Mesenchymal Stem Cell for Prevention and Management of Intervertebral Disc Degeneration. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1030051
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030051