Effects of Cryotherapy on the Maxillary Antrostomy Patency in a Rabbit Model of Chronic Rhinosinusitis
Joint Authors
Taulescu, Marian A.
Albu, Silviu
Gocea, Anamaria
Trombitas, Veronica
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
It is acknowledged that many causes of failures in endoscopic sinus surgery are related to scarring and narrowing of the maxillary antrostomy.
We assessed the effect of low-pressure spray cryotherapy in preventing the maxillary antrostomy stenosis in a chronic rhinosinusitis (CRS) rabbit model.
A controlled, randomized, double-blind study was conducted on 22 New Zealand rabbits.
After inducing unilateral rhinogenic CRS, a maxillary antrostomy was performed and spray cryotherapy was employed on randomly selected 12 rabbits, while saline solution was applied to the control group (n=10).
The antrostomy dimensions and the histological scores were assessed 4 weeks postoperatively.
The diameter of cryotreated antrostomy was significantly larger at 4 weeks than that in the control group.
At 4 weeks, the maxillary antrostomy area in the study group was significantly larger than the mean area in the control group (103.92 ± 30.39 mm2 versus 61.62 ± 28.35 mm2, P=0.002).
Submucosal fibrous tissues and leukocytic infiltration in saline-treated ostia were more prominent than those in cryotreated ostia with no significant differences between the two groups regarding the histological scores.
Intraoperative low-pressure spray cryotherapy increases the patency of the maxillary antrostomy at 4 weeks postoperatively with no important local side effects.
American Psychological Association (APA)
Gocea, Anamaria& Taulescu, Marian A.& Trombitas, Veronica& Albu, Silviu. 2013. Effects of Cryotherapy on the Maxillary Antrostomy Patency in a Rabbit Model of Chronic Rhinosinusitis. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1030068
Modern Language Association (MLA)
Gocea, Anamaria…[et al.]. Effects of Cryotherapy on the Maxillary Antrostomy Patency in a Rabbit Model of Chronic Rhinosinusitis. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1030068
American Medical Association (AMA)
Gocea, Anamaria& Taulescu, Marian A.& Trombitas, Veronica& Albu, Silviu. Effects of Cryotherapy on the Maxillary Antrostomy Patency in a Rabbit Model of Chronic Rhinosinusitis. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1030068
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030068