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Stress Evaluation in Adult Patients with Atopic Dermatitis Using Salivary Cortisol
Joint Authors
Furuichi, Megumi
Yamaguchi, Masaki
Shimizu, Tadamichi
Ueda, Chieko
Makino, Teruhiko
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The symptoms of atopic dermatitis (AD) are often aggravated by stress, and AD can also lead to psychological stress due to social isolation and discrimination.
The salivary cortisol level reflects psychological stress, and it is a good index to assess chronic stress.
In this study, we measured the salivary cortisol levels in patients with AD (n=30) and compared them with those of healthy control subjects (n=42).
AD patients were also evaluated for general disease severity using the Scoring Atopic Dermatitis (SCORAD) index.
The serum levels of TARC, total IgE, and lactate dehydrogenase (LDH) and peripheral blood eosinophil counts were measured by laboratory tests.
The Skindex-16 was used as a skin disease-specific, quality of life measure, instrument.
The results showed that the saliva cortisol level was significantly higher in AD patients compared to healthy subjects (P<0.01).
The salivary cortisol level was significantly correlated with the SCORAD index (r=0.42, P<0.05) while the serum TARC and LDH levels were positively correlated with the SCORAD index.
However, no statistically significant correlations were observed between the salivary cortisol level and Skindex-16.
These results suggest that the saliva cortisol level is therefore a useful biomarker to evaluate the stress in AD patients.
American Psychological Association (APA)
Furuichi, Megumi& Yamaguchi, Masaki& Ueda, Chieko& Makino, Teruhiko& Shimizu, Tadamichi. 2013. Stress Evaluation in Adult Patients with Atopic Dermatitis Using Salivary Cortisol. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030102
Modern Language Association (MLA)
Furuichi, Megumi…[et al.]. Stress Evaluation in Adult Patients with Atopic Dermatitis Using Salivary Cortisol. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1030102
American Medical Association (AMA)
Furuichi, Megumi& Yamaguchi, Masaki& Ueda, Chieko& Makino, Teruhiko& Shimizu, Tadamichi. Stress Evaluation in Adult Patients with Atopic Dermatitis Using Salivary Cortisol. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030102