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Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation
Joint Authors
Chen, Mingyi
Krishnamurthy, Amrita
Mohamed, Ali R.
Green, Ralph
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Obesity and the associated metabolic syndrome are among the most common and detrimental metabolic diseases of the modern era, affecting over 50% of the adult population in the United States.
Surgeries designed to promote weight loss, known as bariatric surgery, typically involve a gastric bypass procedure and have shown high success rates for treating morbid obesity.
However, following gastric bypass surgery, many patients develop chronic anemia, most commonly due to iron deficiency.
Deficiencies of vitamins B1, B12, folate, A, K, D, and E and copper have also been reported after surgery.
Copper deficiency can cause hematological abnormalities with or without neurological complications.
Despite oral supplementation and normal serum concentrations of iron, copper, folate, and vitamin B12, some patients present with persistent anemia after surgery.
The evaluation of hematologic disorders after gastric bypass surgery must take into account issues unique to the postsurgery setting that influence the development of anemia and other cytopenias.
In this paper, the clinical characteristics and differential diagnosis of the hematological disorders associated with gastric bypass surgery are reviewed, and the underlying molecular mechanisms are discussed.
American Psychological Association (APA)
Chen, Mingyi& Krishnamurthy, Amrita& Mohamed, Ali R.& Green, Ralph. 2013. Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030195
Modern Language Association (MLA)
Chen, Mingyi…[et al.]. Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1030195
American Medical Association (AMA)
Chen, Mingyi& Krishnamurthy, Amrita& Mohamed, Ali R.& Green, Ralph. Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030195