Probiotics as Additives on Therapy in Allergic Airway Diseases: A Systematic Review of Benefits and Risks
Joint Authors
Naik, Sushree Samiksha
Singh, Meenu
Das, Rashmi Ranjan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-15
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
We conducted a systematic review to find out the role of probiotics in treatment of allergic airway diseases.
Methods.
A comprehensive search of the major electronic databases was done till March 2013.
Trials comparing the effect of probiotics versus placebo were included.
A predefined set of outcome measures were assessed.
Continuous data were expressed as standardized mean difference with 95% CI.
Dichotomous data were expressed as odds ratio with 95% CI.
P value < 0.05 was considered as significant.
Results.
A total of 12 studies were included.
Probiotic intake was associated with a significantly improved quality of life score in patients with allergic rhinitis (SMD −1.9 (95% CI −3.62, −0.19); P = 0.03), though there was a high degree of heterogeneity.
No improvement in quality of life score was noted in asthmatics.
Probiotic intake also improved the following parameters: longer time free from episodes of asthma and rhinitis and decrease in the number of episodes of rhinitis per year.
Adverse events were not significant.
Conclusion.
As the current evidence was generated from few trials with high degree of heterogeneity, routine use of probiotics as an additive on therapy in subjects with allergic airway diseases cannot be recommended.
American Psychological Association (APA)
Das, Rashmi Ranjan& Naik, Sushree Samiksha& Singh, Meenu. 2013. Probiotics as Additives on Therapy in Allergic Airway Diseases: A Systematic Review of Benefits and Risks. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030209
Modern Language Association (MLA)
Das, Rashmi Ranjan…[et al.]. Probiotics as Additives on Therapy in Allergic Airway Diseases: A Systematic Review of Benefits and Risks. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030209
American Medical Association (AMA)
Das, Rashmi Ranjan& Naik, Sushree Samiksha& Singh, Meenu. Probiotics as Additives on Therapy in Allergic Airway Diseases: A Systematic Review of Benefits and Risks. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030209
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030209