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Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues
Joint Authors
Sequeiros, Tamara
García, Marta
Montes, Melania
Oliván, Mireia
Rigau, Marina
Colás, Eva
de Torres, Inés
Reventós, Jaume
Morote, Juan
Doll, Andreas
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-25
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Prostate cancer (PCa) is the most frequently diagnosed type of cancer in developed countries.
The decisive method of diagnosis is based on the results of biopsies, morphologically evaluated to determine the presence or absence of cancer.
Although this approach leads to a confident diagnosis in most cases, it can be improved by using the molecular markers present in the tissue.
Both miRNAs and proteins are considered excellent candidates for biomarkers in formalin-fixed paraffin-embedded (FFPE) tissues, due to their stability over long periods of time.
In the last few years, a concerted effort has been made to develop the necessary tools for their reliable measurement in these types of samples.
Furthermore, the use of these kinds of markers may also help in establishing tumor grade and aggressiveness, as well as predicting the possible outcomes in each particular case for the different treatments available.
This would aid clinicians in the decision-making process.
In this review, we attempt to summarize and discuss the potential use of microRNA and protein profiles in FFPE tissue samples as markers to better predict PCa diagnosis, progression, and response to therapy.
American Psychological Association (APA)
Sequeiros, Tamara& García, Marta& Montes, Melania& Oliván, Mireia& Rigau, Marina& Colás, Eva…[et al.]. 2013. Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1030293
Modern Language Association (MLA)
Sequeiros, Tamara…[et al.]. Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1030293
American Medical Association (AMA)
Sequeiros, Tamara& García, Marta& Montes, Melania& Oliván, Mireia& Rigau, Marina& Colás, Eva…[et al.]. Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1030293
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030293