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Heparin and Carboxymethylchitosan Metal Nanoparticles: An Evaluation of Their Cytotoxicity
Joint Authors
Bava, Adriana
Cappellini, Francesca
Pedretti, Elisa
Rossi, Federica
Caruso, Enrico
Vismara, Elena
Bernardini, Giovanni
Gornati, Rosalba
Chiriva-Internati, Maurizio
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
In the search for noninvasive diagnostic techniques and new therapies, “nanosystems”, which are capable of binding and targeting bioactive molecules, are becoming increasingly important.
In this context, biocompatible coatings are gaining interest, not only for their biological effects but also because they are considered capable to mask nanoparticle toxicity.
In this work, we have compared the toxicity of nanoparticles coated with heparin and carboxymethylchitosan in the SKOV-3 cell line.
Our results indicate that heparin and carboxymethylchitosan coatings do not guarantee the decrease of nanoparticle intrinsic toxicity which is often envisaged.
Nonetheless, these coatings provide the opportunity for further functionalization with a variety of biomolecules for their use in theranostics.
American Psychological Association (APA)
Bava, Adriana& Cappellini, Francesca& Pedretti, Elisa& Rossi, Federica& Caruso, Enrico& Vismara, Elena…[et al.]. 2013. Heparin and Carboxymethylchitosan Metal Nanoparticles: An Evaluation of Their Cytotoxicity. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030357
Modern Language Association (MLA)
Bava, Adriana…[et al.]. Heparin and Carboxymethylchitosan Metal Nanoparticles: An Evaluation of Their Cytotoxicity. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030357
American Medical Association (AMA)
Bava, Adriana& Cappellini, Francesca& Pedretti, Elisa& Rossi, Federica& Caruso, Enrico& Vismara, Elena…[et al.]. Heparin and Carboxymethylchitosan Metal Nanoparticles: An Evaluation of Their Cytotoxicity. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030357
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030357