Biological Activities and Pharmacokinetics of Praeruptorins from Peucedanum Species: A Systematic Review
Joint Authors
Shafiee, Abbas
Sarkheil, Pantea
Sarkhail, Parisa
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Praeruptorins belonging to the angular-type pyranocoumarins are bioactive constituents that have been isolated from some Peucedanum species such as P.
praeruptorum, which is used in traditional Chinese medicine for treatment of cold, cough, upper respiratory infections, and so forth.
Many reports have demonstrated that the beneficial pharmacological effects of P.
praeruptorum root on cardiovascular, pulmonary, immune, and nervous system diseases were attributed to the presence of praeruptorins.
The aim of this review is to explain the recent efforts of scientists in pharmacological screening of natural and synthetic praeruptorin derivatives, studying the mechanisms of some praeruptorins action, pharmacokinetics, toxicity, and relevant structure-activity relationships.
Based on reported data about the pharmacological properties of praeruptorins and semisynthetic derivatives of them, it is hopeful that in the near future more studies focus on the discovery of the new application and therapeutic uses of these bioactive compounds and understanding the specific mechanisms of them.
The present discusses the reports on molecular and biological activities of praeruptorins of the genus Peucedanum, from 1976 onwards.
American Psychological Association (APA)
Sarkhail, Parisa& Shafiee, Abbas& Sarkheil, Pantea. 2013. Biological Activities and Pharmacokinetics of Praeruptorins from Peucedanum Species: A Systematic Review. BioMed Research International،Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-1030415
Modern Language Association (MLA)
Sarkhail, Parisa…[et al.]. Biological Activities and Pharmacokinetics of Praeruptorins from Peucedanum Species: A Systematic Review. BioMed Research International No. 2013 (2013), pp.1-14.
https://search.emarefa.net/detail/BIM-1030415
American Medical Association (AMA)
Sarkhail, Parisa& Shafiee, Abbas& Sarkheil, Pantea. Biological Activities and Pharmacokinetics of Praeruptorins from Peucedanum Species: A Systematic Review. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-1030415
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030415