Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities
Joint Authors
Ali, M.
Rasul, Azhar
Millimouno, Faya Martin
Ali Eltayb, Wafa
Li, Jiang
Li, Xiaomeng
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Pinocembrin (5,7-dihydroxyflavanone) is one of the primary flavonoids isolated from the variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and Sparattosperma leucanthum, in the diverse flora and purified by various chromatographic techniques.
Pinocembrin is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry.
Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.
In addition, pinocembrin can be used as neuroprotective against cerebral ischemic injury with a wide therapeutic time window, which may be attributed to its antiexcitotoxic effects.
Pinocembrin exhibits pharmacological effects on almost all systems, and our aim is to review the pharmacological and therapeutic applications of pinocembrin with specific emphasis on mechanisms of actions.
The design of new drugs based on the pharmacological effects of pinocembrin could be beneficial.
This review suggests that pinocembrin is a potentially promising pharmacological candidate, but additional studies and clinical trials are required to determine its specific intracellular sites of action and derivative targets in order to fully understand the mechanism of its anti-inflammatory, anticancer, and apoptotic effects to further validate its medical applications.
American Psychological Association (APA)
Rasul, Azhar& Millimouno, Faya Martin& Ali Eltayb, Wafa& Ali, M.& Li, Jiang& Li, Xiaomeng. 2013. Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030460
Modern Language Association (MLA)
Rasul, Azhar…[et al.]. Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1030460
American Medical Association (AMA)
Rasul, Azhar& Millimouno, Faya Martin& Ali Eltayb, Wafa& Ali, M.& Li, Jiang& Li, Xiaomeng. Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030460
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030460