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Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images
Joint Authors
Kao, Yi-Hsuan
Teng, Michael Mu Huo
Cho, I-Chieh
Chuang, Chi-Shuo
Chiu, Fang-Ying
Chang, Feng-Chi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
To improve the quantitative assessment of cerebral blood volume (CBV) and flow (CBF) in the brain voxels from MR perfusion images.
Materials and Methods.
Normal brain parenchyma was automatically segmented with the time-to-peak criteria after cerebrospinal fluid removal and preliminary vessel voxel removal.
Two scaling factors were calculated by comparing the relative CBV and CBF of the segmented normal brain parenchyma with the absolute values in the literature.
Using the scaling factors, the relative values were converted to the absolute CBV and CBF.
Voxels with either CBV > 8 mL/100 g or CBF > 100 mL/100 g/min were characterized as vessel voxels and were excluded from the quantitative measurements.
Results.
The segmented brain parenchyma with normal perfusion was consistent with the angiographic findings for each patient.
We confirmed the necessity of dual thresholds including CBF and CBV for proper removal of vessel voxels.
The scaling factors were 0.208 ± 0.041 for CBV, and 0.168 ± 0.037, 0.172 ± 0.037 for CBF calculated using standard and circulant singular value decomposition techniques, respectively.
Conclusion.
The automatic scaling and vessel removal techniques provide an alternative method for obtaining improved quantitative assessment of CBV and CBF in patients with thromboembolic cerebral arterial disease.
American Psychological Association (APA)
Teng, Michael Mu Huo& Cho, I-Chieh& Kao, Yi-Hsuan& Chuang, Chi-Shuo& Chiu, Fang-Ying& Chang, Feng-Chi. 2013. Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030465
Modern Language Association (MLA)
Teng, Michael Mu Huo…[et al.]. Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1030465
American Medical Association (AMA)
Teng, Michael Mu Huo& Cho, I-Chieh& Kao, Yi-Hsuan& Chuang, Chi-Shuo& Chiu, Fang-Ying& Chang, Feng-Chi. Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030465
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030465