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New Bioactive Fungal Molecules with High Antioxidant and Antimicrobial Capacity Isolated from Cerrena unicolor Idiophasic Cultures
Joint Authors
Janusz, Grzegorz
Osińska-Jaroszuk, Monika
Matuszewska, Anna
Stefaniuk, Dawid
Sulej, Justyna
Ruminowicz, Marta
Grzywnowicz, Krzysztof
Jarosz-Wilkołazka, Anna
Polak, Jolanta
Jaszek, Magdalena
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-15
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Three bioactive fractions, extracellular laccase (ex-LAC), crude endopolysaccharides (c-EPL), and a low molecular subfraction of secondary metabolites (ex-LMS), were isolated from the idiophasic cultures of the white rot fungus Cerrena unicolor.
For the first time, we determined the antioxidant properties of these samples by chemiluminometric measurement (a) and assessment of the scavenging effect on ABTS (b) and the DPPH reduction rate (c).
The highest reducing capability was found for the ex-LMS fraction: 39–90% for (a), 20–90% for (b), and 10–59% for (c) at the concentration of 6.25–800 µg/mL.
The scavenging abilities of the C.
unicolor c-EPL were between 36 and 70% for (a), 2 and 60% for (b), and 28 and 32% for (c) at the concentration of 6.25–800 µg/mL.
A very high prooxidative potential was observed for the ex-LAC probes.
The preliminary toxicity tests were done using the Microtox system and revealed the following percentage of the toxic effect against Vibrio fischeri: 85.37% for c-EPL, 50.67% for ex-LAC, and 99.8% for ex-LMS, respectively.
The ex-LAC sample showed the antibacterial activity against Escherichia coli, c-EPL against Staphylococcus aureus, and ex-LMS against both bacterial strains, respectively, but the stronger inhibitory effect was exerted on S.
aureus.
American Psychological Association (APA)
Jaszek, Magdalena& Osińska-Jaroszuk, Monika& Janusz, Grzegorz& Matuszewska, Anna& Stefaniuk, Dawid& Sulej, Justyna…[et al.]. 2013. New Bioactive Fungal Molecules with High Antioxidant and Antimicrobial Capacity Isolated from Cerrena unicolor Idiophasic Cultures. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030600
Modern Language Association (MLA)
Jaszek, Magdalena…[et al.]. New Bioactive Fungal Molecules with High Antioxidant and Antimicrobial Capacity Isolated from Cerrena unicolor Idiophasic Cultures. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1030600
American Medical Association (AMA)
Jaszek, Magdalena& Osińska-Jaroszuk, Monika& Janusz, Grzegorz& Matuszewska, Anna& Stefaniuk, Dawid& Sulej, Justyna…[et al.]. New Bioactive Fungal Molecules with High Antioxidant and Antimicrobial Capacity Isolated from Cerrena unicolor Idiophasic Cultures. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030600