A New Parasiticidal Compound in T. solium Cysticercosis
Joint Authors
Morales-Montor, Jorge
Hernández-Bello, Romel
Carrero, Julio Cesar
Cervantes-Rebolledo, Claudia
Dowding, Charles
Frincke, James
Reading, Chris
Escobedo, Galileo
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The effect of 16α-bromoepiandrosterone (EpiBr), a dehydroepiandrosterone (DHEA) analogue, was tested on the cysticerci of Taenia solium, both in vitro and in vivo.
In vitro treatment of T.
solium cultures with EpiBr reduced scolex evagination, growth, motility, and viability in dose- and time-dependent fashions.
Administration of EpiBr prior to infection with T.
solium cysticerci in hamsters reduced the number and size of developed taenias in the intestine, compared with controls.
These effects were associated to an increase in splenocyte proliferation in infected hamsters.
These results leave open the possibility of assessing the potential of this hormonal analogue as a possible antiparasite drug, particularly in cysticercosis and taeniosis.
American Psychological Association (APA)
Hernández-Bello, Romel& Escobedo, Galileo& Carrero, Julio Cesar& Cervantes-Rebolledo, Claudia& Dowding, Charles& Frincke, James…[et al.]. 2012. A New Parasiticidal Compound in T. solium Cysticercosis. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030610
Modern Language Association (MLA)
Hernández-Bello, Romel…[et al.]. A New Parasiticidal Compound in T. solium Cysticercosis. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1030610
American Medical Association (AMA)
Hernández-Bello, Romel& Escobedo, Galileo& Carrero, Julio Cesar& Cervantes-Rebolledo, Claudia& Dowding, Charles& Frincke, James…[et al.]. A New Parasiticidal Compound in T. solium Cysticercosis. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030610
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030610