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In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts
Joint Authors
Teh, Soek Sin
Mah, Siau Hui
Ahmad, Zuraini
Lim, Yang Mooi
Ee, Gwendoline Cheng Lian
Yong, Yoke Keong
Rahmani, Mawardi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The in vitro cytotoxicity tests on the extracts of Mesua beccariana, M.
ferrea, and M.
congestiflora against Raji, SNU-1, HeLa, LS-174T, NCI-H23, SK-MEL-28, Hep-G2, IMR-32, and K562 were achieved using MTT assay.
The methanol extracts of Mesua beccariana showed its potency towards the proliferation of B-lymphoma cell (Raji).
In addition, only the nonpolar to semipolar extracts (hexane to ethyl acetate) of the three Mesua species indicated cytotoxic effects on the tested panel of human cancer cell lines.
Antioxidant assays were evaluated using DPPH scavenging radical assay and Folin-Ciocalteu method.
The methanol extracts of M.
beccariana and M.
ferrea showed high antioxidant activities with low EC50 values of 12.70 and 9.77 μg/mL, respectively, which are comparable to that of ascorbic acid (EC50 = 5.62 μg/mL).
Antibacterial tests were carried out using four Gram positive and four Gram negative bacteria on Mesua beccariana extracts.
All the extracts showed negative results in the inhibition of Gram negative bacteria.
Nevertheless, methanol extracts showed some activities against Gram positive bacteria which are Bacillus cereus, methicillin-sensitive Staphylococcus aureus (MSSA), and methicillin-resistant Staphylococcus aureus (MRSA), while the hexane extract also contributed some activities towards Bacillus cereus.
American Psychological Association (APA)
Teh, Soek Sin& Ee, Gwendoline Cheng Lian& Mah, Siau Hui& Yong, Yoke Keong& Lim, Yang Mooi& Rahmani, Mawardi…[et al.]. 2013. In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030616
Modern Language Association (MLA)
Teh, Soek Sin…[et al.]. In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1030616
American Medical Association (AMA)
Teh, Soek Sin& Ee, Gwendoline Cheng Lian& Mah, Siau Hui& Yong, Yoke Keong& Lim, Yang Mooi& Rahmani, Mawardi…[et al.]. In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030616
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030616