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Monounsaturated Fatty Acids Are Substrates for Aldehyde Generation in Tellurite-Exposed Escherichia coli
Joint Authors
Pradenas, Gonzalo A.
Díaz-Vásquez, Waldo A.
Vásquez, Claudio C.
Pérez-Donoso, José M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts.
In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial resistance to oxidative stress elicitors was evaluated.
Studies included wild-type cells as well as cells exhibiting a modulated monounsaturated fatty acid (MUFA) ratio.
The hydroxyaldehyde 4-hydroxy 2-nonenal was found to be most likely produced by E.
coli, whose levels are dependent upon exposure to oxidative stress elicitors.
Aldehyde amounts and markers of oxidative damage decreased upon exposure to E.
coli containing low MUFA ratios, which was paralleled by a concomitant increase in resistance to ROS-generating compounds.
MUFAs ratio, lipid peroxidation, and aldehyde generation were found to be directly related; that is, the lower the MUFAs ratio, the lower the peroxide and aldehyde generation levels.
These results provide additional evidence about MUFAs being targets for membrane lipid oxidation and their relevance in aldehyde generation.
American Psychological Association (APA)
Pradenas, Gonzalo A.& Díaz-Vásquez, Waldo A.& Pérez-Donoso, José M.& Vásquez, Claudio C.. 2013. Monounsaturated Fatty Acids Are Substrates for Aldehyde Generation in Tellurite-Exposed Escherichia coli. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1030662
Modern Language Association (MLA)
Pradenas, Gonzalo A.…[et al.]. Monounsaturated Fatty Acids Are Substrates for Aldehyde Generation in Tellurite-Exposed Escherichia coli. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1030662
American Medical Association (AMA)
Pradenas, Gonzalo A.& Díaz-Vásquez, Waldo A.& Pérez-Donoso, José M.& Vásquez, Claudio C.. Monounsaturated Fatty Acids Are Substrates for Aldehyde Generation in Tellurite-Exposed Escherichia coli. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1030662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030662