In Vitro and In Vivo Survival and Colonic Adhesion of Pediococcus acidilactici MTCC5101 in Human Gut
Joint Authors
Kaur, Baljinder
Balgir, Praveen P.
Kaur, Tejinder
Daroch, Natisha
Kaur, Gurpreet
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The present study aims to investigate the probiotic nature of Pediococcus acidilactici MTCC5101 by an in vitro assay of bacterial adherence to intestinal epithelial cells of human gastrointestinal (GI) tract using Caco-2 cell line.
Further to assess the in vivo survival in the GI tract, oral feeding was carried out with the help of 10 healthy volunteers.
The effect on wellness was assessed by studying blood biochemical parameters of the volunteers.
The survival of the bacteria was assessed using PCR-based detection of P.
acidilactici MTCC5101 in fecal samples.
The probiotic nature of P.
acidilactici MTCC 5101 was strengthened by its adherence to the intestinal epithelial Caco-2 cell line in the in vitro SEM observations.
Oral feeding study for assessing the survival of bacteria in GI tract of volunteers showed the strain to be established in the GI tract which survived for about 2 weeks after feeding.
American Psychological Association (APA)
Balgir, Praveen P.& Kaur, Baljinder& Kaur, Tejinder& Daroch, Natisha& Kaur, Gurpreet. 2013. In Vitro and In Vivo Survival and Colonic Adhesion of Pediococcus acidilactici MTCC5101 in Human Gut. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030686
Modern Language Association (MLA)
Balgir, Praveen P.…[et al.]. In Vitro and In Vivo Survival and Colonic Adhesion of Pediococcus acidilactici MTCC5101 in Human Gut. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1030686
American Medical Association (AMA)
Balgir, Praveen P.& Kaur, Baljinder& Kaur, Tejinder& Daroch, Natisha& Kaur, Gurpreet. In Vitro and In Vivo Survival and Colonic Adhesion of Pediococcus acidilactici MTCC5101 in Human Gut. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030686
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030686