Mitochondria and Cancer: Past, Present, and Future
Joint Authors
Harbottle, Andrew
Parr, Ryan
Verschoor, M. L.
Ungard, R.
Jakupciak, J. P.
Singh, Gurmit
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The area of mitochondrial genomics has undergone unprecedented growth over the past several years.
With the advent of the age of omics, investigations have reached beyond the nucleus to encompass the close biological communication and finely coordinated interactions between mitochondria and their nuclear cell mate.
Application of this holistic approach, to all metabolic interactions within the cell, is providing a more complete understanding of the molecular transformation of the cell from normal to malignant behavior, before histopathological indications are evident.
In this review the surging momentum in mitochondrial science, as it relates to cancer, is described in three progressive perspectives: (1) Past: the historical contributions to current directions of research; (2) Present: Contemporary findings, results and approaches to mitochondria and cancer, including the role of next generation sequencing and proteomics; (3) Future: Based on the present body of knowledge, the potential assets and benefits of mitochondrial research are projected into the near future.
American Psychological Association (APA)
Verschoor, M. L.& Ungard, R.& Harbottle, Andrew& Jakupciak, J. P.& Parr, Ryan& Singh, Gurmit. 2013. Mitochondria and Cancer: Past, Present, and Future. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030718
Modern Language Association (MLA)
Verschoor, M. L.…[et al.]. Mitochondria and Cancer: Past, Present, and Future. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030718
American Medical Association (AMA)
Verschoor, M. L.& Ungard, R.& Harbottle, Andrew& Jakupciak, J. P.& Parr, Ryan& Singh, Gurmit. Mitochondria and Cancer: Past, Present, and Future. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030718