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Effects of Processing and Storage on Pediococcus pentosaceus SB83 in Vaginal Formulations: Lyophilized Powder and Tablets
Joint Authors
Costa, Paulo
Borges, Sandra
Teixeira, Paula
Silva, Joana
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Vaginal probiotics have an important role in preventing the colonization of the vagina by pathogens.
This study aimed to investigate different formulations with Pediococcus pentosaceus SB83 (lyophilized powder and tablets with and without retarding polymer) in order to verify its stability and antilisterial activity after manufacture and during storage.
The bacteriocinogenic activity of P.
pentosaceus SB83 against Listeria monocytogenes was evaluated in simulated vaginal fluid.
Suspension of Pediococcus pentosaceus SB83 reduced the pathogen only after 2 h and the lyophilized bacteria after 24 h of contact, and, in the tablets, P.
pentosaceus SB83 lost the antimicrobial activity.
The pH of simulated vaginal fluid decreased for all the tested conditions.
As lyophilized powder demonstrated better results concerning antimicrobial activity, this formulation was selected to evaluate the antilisterial activity during the 12 months of storage.
During storage at room temperature, lyophilized bacteria totally inhibited the pathogen only until one month of storage.
At 4°C, P.
pentosaceus SB83 showed antimicrobial activity during all the time of storage investigated.
Therefore, the better formulation of P.
pentosaceus SB83 is the lyophilized powder stored at 4°C, which may be administered intravaginally as a washing solution.
American Psychological Association (APA)
Borges, Sandra& Costa, Paulo& Silva, Joana& Teixeira, Paula. 2013. Effects of Processing and Storage on Pediococcus pentosaceus SB83 in Vaginal Formulations: Lyophilized Powder and Tablets. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030782
Modern Language Association (MLA)
Borges, Sandra…[et al.]. Effects of Processing and Storage on Pediococcus pentosaceus SB83 in Vaginal Formulations: Lyophilized Powder and Tablets. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1030782
American Medical Association (AMA)
Borges, Sandra& Costa, Paulo& Silva, Joana& Teixeira, Paula. Effects of Processing and Storage on Pediococcus pentosaceus SB83 in Vaginal Formulations: Lyophilized Powder and Tablets. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030782
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030782