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Chemical Composition and Antibacterial and Cytotoxic Activities of Allium hirtifolium Boiss
Joint Authors
Shameli, Kamyar
Ismail, Salmiah
Jalilian, Farid Azizi
Talebpour, Amir Hossein
Zargar, Mohsen
Jahanshiri, Fatemeh
Sekawi, Zamberi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Allium hirtifolium Boiss.
known as Persian shallot, is a spice used as a traditional medicine in Iran and, Mediterranean region.
In this study, the chemical composition of the hydromethanolic extract of this plant was analyzed using GC/MS.
The result showed that 9-hexadecenoic acid, 11,14-eicosadienoic acid, and n-hexadecanoic acid are the main constituents.
The antibacterial activity of the shallot extract was also examined by disk diffusion and microdilution broth assays.
It was demonstrated that Persian shallot hydromethanolic extract was effective against 10 different species of pathogenic bacteria including methicillin resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphylococcus aureus (MSSA), Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Proteus mirabilis, and Klebsiella pneumoniae.
Specifically, the minimum concentration of the extract which inhibited bacterial growth (MIC values) was 1.88 mg/mL for most of the gram-positive bacteria.
This concentration was not much different from the concentration that was safe for mammalian cells (1.50 mg/mL) suggesting that the hydromethanolic extract of Persian shallot may be a safe and strong antibacterial agent.
American Psychological Association (APA)
Ismail, Salmiah& Jalilian, Farid Azizi& Talebpour, Amir Hossein& Zargar, Mohsen& Shameli, Kamyar& Sekawi, Zamberi…[et al.]. 2012. Chemical Composition and Antibacterial and Cytotoxic Activities of Allium hirtifolium Boiss. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030805
Modern Language Association (MLA)
Ismail, Salmiah…[et al.]. Chemical Composition and Antibacterial and Cytotoxic Activities of Allium hirtifolium Boiss. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1030805
American Medical Association (AMA)
Ismail, Salmiah& Jalilian, Farid Azizi& Talebpour, Amir Hossein& Zargar, Mohsen& Shameli, Kamyar& Sekawi, Zamberi…[et al.]. Chemical Composition and Antibacterial and Cytotoxic Activities of Allium hirtifolium Boiss. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030805
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030805