A Comparison between 18F-FDG PETCT Imaging and Biological and Radiological Findings in Restaging of Hepatoblastoma Patients
Joint Authors
Treglia, Giorgio
Fagioli, Franca
Pagano, Manuela
Fania, Piercarlo
Bova, Valentina
Basso, Maria Eleonora
Ficola, Umberto
Cistaro, Angelina
Quartuccio, Natale
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
In this study we retrospectively evaluated if 18F-FDG-PET/CT provided incremental diagnostic information over CI in a group of hepatoblastoma patients performing restaging.
Procedure.
Nine patients (mean age: 5.9 years; range: 3.1–12 years) surgically treated for hepatoblastoma were followed up by clinical examination, serum α-FP monitoring, and US.
CI (CT or MRI) and PET/CT were performed in case of suspicion of relapse.
Fine-needle aspiration biopsies (FNAB) were carried out for final confirmation if the results of CI, PET/CT, and/or α-FP levels were suggestive of relapse.
PET/CT and CI findings were analyzed for comparison purposes, using FNAB as reference standard.
Results.
α-FP level was suggestive of disease recurrence in 8/9 patients.
Biopsy was performed in 8/9 cases.
CI and PET/CT resulted to be concordant in 5/9 patients (CI identified recurrence of disease, but 18F-FDG-PET/CT provided a better definition of disease extent); in 4/9 cases, CI diagnostic information resulted in negative findings, whereas PET/CT correctly detected recurrence of disease.
18F-FDG-PET/CT showed an agreement of 100% (8/8) with FNAB results.
Conclusions.
18F-FDG-PET/CT scan seems to better assess HB patients with respect to CI and may provide incremental diagnostic value in the restaging of this group of patients.
American Psychological Association (APA)
Cistaro, Angelina& Treglia, Giorgio& Pagano, Manuela& Fania, Piercarlo& Bova, Valentina& Basso, Maria Eleonora…[et al.]. 2013. A Comparison between 18F-FDG PETCT Imaging and Biological and Radiological Findings in Restaging of Hepatoblastoma Patients. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1030822
Modern Language Association (MLA)
Cistaro, Angelina…[et al.]. A Comparison between 18F-FDG PETCT Imaging and Biological and Radiological Findings in Restaging of Hepatoblastoma Patients. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1030822
American Medical Association (AMA)
Cistaro, Angelina& Treglia, Giorgio& Pagano, Manuela& Fania, Piercarlo& Bova, Valentina& Basso, Maria Eleonora…[et al.]. A Comparison between 18F-FDG PETCT Imaging and Biological and Radiological Findings in Restaging of Hepatoblastoma Patients. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1030822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030822