Helical Irradiation of the Total Skin with Dose Painting to Replace Total Skin Electron Beam Therapy for Therapy-Refractory Cutaneous CD4+ T-Cell Lymphoma
Joint Authors
Hsieh, Chen-Hsi
Shiau, An-Cheng
Tien, Hui-Ju
Lin, Shih-Chiang
Shueng, Pei-Wei
Chou, Yueh-Hung
Wu, Meng-Hao
Wang, Jen-Yu
Chen, Chi-Kuan
Chen, Yu-Jen
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-23
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
A 36-year-old woman was diagnosed with a therapy-refractory cutaneous CD4+ T-cell lymphoma, T3N0M0B0, and stage IIB.
Helical irradiation of the total skin (HITS) and dose painting techniques, with 30 Gy in 40 fractions interrupted at 20 fractions with one week resting, 4 times per week were prescribed.
The diving suit was dressed whole body to increase the superficial dose and using central core complete block (CCCB) technique for reducing the internal organ dose.
The mean doses of critical organs of head, chest, and abdomen were 2.1 to 29.9 Gy, 2.9 to 8.1 Gy, and 3.6 to 15.7 Gy, respectively.
The mean dose of lesions was 84.0 cGy.
The dosage of left side pretreated area was decreased 57%.
The tumor regressed progressively without further noduloplaques.
During the HITS procedure, most toxicity was grade I except leukocytopenia with grade 3.
No epitheliolysis, phlyctenules, tumor lysis syndrome, fever, vomiting, dyspnea, edema of the extremities, or diarrhea occurred during the treatment.
HITS with dose painting techniques provides precise dosage delivery with impressive results, sparing critical organs, and offering limited transient and chronic sequelae for previously locally irradiated, therapy-refractory cutaneous T-cell lymphoma.
American Psychological Association (APA)
Hsieh, Chen-Hsi& Shueng, Pei-Wei& Lin, Shih-Chiang& Tien, Hui-Ju& Shiau, An-Cheng& Chou, Yueh-Hung…[et al.]. 2013. Helical Irradiation of the Total Skin with Dose Painting to Replace Total Skin Electron Beam Therapy for Therapy-Refractory Cutaneous CD4+ T-Cell Lymphoma. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030832
Modern Language Association (MLA)
Hsieh, Chen-Hsi…[et al.]. Helical Irradiation of the Total Skin with Dose Painting to Replace Total Skin Electron Beam Therapy for Therapy-Refractory Cutaneous CD4+ T-Cell Lymphoma. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1030832
American Medical Association (AMA)
Hsieh, Chen-Hsi& Shueng, Pei-Wei& Lin, Shih-Chiang& Tien, Hui-Ju& Shiau, An-Cheng& Chou, Yueh-Hung…[et al.]. Helical Irradiation of the Total Skin with Dose Painting to Replace Total Skin Electron Beam Therapy for Therapy-Refractory Cutaneous CD4+ T-Cell Lymphoma. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030832
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030832