Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia
Joint Authors
Piérard, Gérald E.
Loussouarn, Geneviève
Panhard, Ségolène
Saint Léger, Didier
Mellul, Myriam
Piérard-Franchimont, Claudine
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Skin ageing and gender influences on the scalp have been seldom studied.
We revisited the changes in the interfollicular scalp.
The study was performed on a population of 650 volunteers (300 women and 350 men) for over 7 years.
Three age groups were selected in both genders, namely, subjects aged 20–35, 50–60, and 60–70 years.
The hair status was further considered according to nonalopecic and alopecic patterns and severity (discrete, moderate, and severe).
Biopsies from the parietal area were processed for immunohistochemistry.
Stromal cells were distinguished according to the presence of vimentin, Factor XIIIa, CD117, and versican.
Blood and lymphatic vessels were highlighted by Ulex europaeus agglutinin-1 and human podoplanin immunoreactivities, respectively.
Actinic elastosis was identified by the lysozyme coating of elastic fibres.
The epidermis was explored using the CD44 variant 3 and Ki67 immunolabellings.
Biplot analyses were performed.
Immunohistochemistry revealed a prominent gender effect in young adults.
Both Factor XIIIa+ dermal dendrocytes and the microvasculature size decreased with scalp ageing.
Alopecia changes mimicked stress-induced premature senescence.
American Psychological Association (APA)
Piérard-Franchimont, Claudine& Loussouarn, Geneviève& Panhard, Ségolène& Saint Léger, Didier& Mellul, Myriam& Piérard, Gérald E.. 2013. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030899
Modern Language Association (MLA)
Piérard-Franchimont, Claudine…[et al.]. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1030899
American Medical Association (AMA)
Piérard-Franchimont, Claudine& Loussouarn, Geneviève& Panhard, Ségolène& Saint Léger, Didier& Mellul, Myriam& Piérard, Gérald E.. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1030899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1030899