New Hypothesis on Pathogenesis of Ovarian Cancer Lead to Future Tailored Approaches
Joint Authors
De Placido, Sabino
Rescigno, P.
Cerillo, I.
Ruocco, R.
Condello, C.
Pensabene, M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-25
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
In the last decades, management of epithelial ovarian cancer (EOC) has been based on the staging system of the International Federation of Gynecology and Obstetrics (FIGO), and different classifications have been proposed for EOC that take account of grade of differentiation, histological subtype, and clinical features.
However, despite taxonomic efforts, EOC appears to be not a unique disease; its subtypes differ for epidemiological and genetic risk factors, precursor lesions, patterns of spread, response to chemotherapy, and prognosis.
Nevertheless, carboplatin plus paclitaxel combination represents the only standard treatment in adjuvant and advanced settings.
This paper summarizes theories about the classification and origin of EOC and classical and new prognostic factors.
It presents data about standard treatment and novel agents.
We speculate about the possibility to create tailored therapy based on specific mutations in ovarian cancer and to personalize prevention.
American Psychological Association (APA)
Rescigno, P.& Cerillo, I.& Ruocco, R.& Condello, C.& De Placido, Sabino& Pensabene, M.. 2013. New Hypothesis on Pathogenesis of Ovarian Cancer Lead to Future Tailored Approaches. BioMed Research International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1031025
Modern Language Association (MLA)
Rescigno, P.…[et al.]. New Hypothesis on Pathogenesis of Ovarian Cancer Lead to Future Tailored Approaches. BioMed Research International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-1031025
American Medical Association (AMA)
Rescigno, P.& Cerillo, I.& Ruocco, R.& Condello, C.& De Placido, Sabino& Pensabene, M.. New Hypothesis on Pathogenesis of Ovarian Cancer Lead to Future Tailored Approaches. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1031025
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031025