Cardiac Contractile Reserve Parameters Are Related to Prognosis in Septic Shock
Joint Authors
Kimmoun, Antoine
Ducrocq, Nicolas
Mory, Sébastien
Delfosse, Remi
Muller, Laura
Fay, Renaud
Levy, Bruno
Perez, Pierre
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
Cardiac reserve could be defined as the spontaneous magnitude from basal to maximal cardiac power under stress conditions.
The aim of this study was to evaluate the prognostic value of cardiac reserve parameters in resuscitated septic shock patients.
Methods.
Seventy patients with septic shock were included in a prospective and observational study.
Prior to inclusion, patients were resuscitated to reach a mean arterial pressure of 65–75 mmHg with an euvolemic status.
General, hemodynamic, and cardiac reserve-related parameters (cardiac index, double product, and cardiac power index) were collected at inclusion and at day 1.
Results.
Seventy patients were included with 28-day mortality at 38.5%.
Ten of the 70 patients died during the first day.
In multivariate analysis, independent predictors of death were SAPS II ≥58 (OR: 3.36 [1.11–10.17]; P=0.032), a high double product at inclusion (OR [95% IC]: 1.20 [1.00–1.45] per 103 mmHg·min; P=0.047), and at day 1, a decrease in cardiac index (1.30 [1.08–1.56] per 0.5 L/min/m2; P=0.007) or cardiac power index (1.84 [1.18–2.87] per 0.1 W/m2, P=0.008).
Conclusion.
In the first 24 hours, parameters related to cardiac reserve, such as double product and cardiac index evolution, provide crucial and easy to achieve hemodynamic physiological information, which may impact the outcome.
American Psychological Association (APA)
Kimmoun, Antoine& Ducrocq, Nicolas& Mory, Sébastien& Delfosse, Remi& Muller, Laura& Perez, Pierre…[et al.]. 2013. Cardiac Contractile Reserve Parameters Are Related to Prognosis in Septic Shock. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031112
Modern Language Association (MLA)
Kimmoun, Antoine…[et al.]. Cardiac Contractile Reserve Parameters Are Related to Prognosis in Septic Shock. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1031112
American Medical Association (AMA)
Kimmoun, Antoine& Ducrocq, Nicolas& Mory, Sébastien& Delfosse, Remi& Muller, Laura& Perez, Pierre…[et al.]. Cardiac Contractile Reserve Parameters Are Related to Prognosis in Septic Shock. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031112
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031112