Bovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes
Joint Authors
Martano, Manuela
Maiolino, Paola
Özkul, Ayhan
Sepici-Dincel, Aylin
Borzacchiello, Giuseppe
Russo, Valeria
Yücel, Gözde
Urraro, Chiara
Lucà, Roberta
Riccardi, Marita Georgia
Esposito, Iolanda
Roperto, Sante
Roperto, Franco Peppino
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Microscopic patterns of thirty-four urothelial tumors of the urinary bladder of water buffaloes from the Marmara and Black Sea Regions of Turkey are here described.
All the animals grazed on lands rich in bracken fern.
Histological diagnosis was assessed using morphological parameters recently suggested for the urinary bladder tumors of cattle.
Papillary carcinoma was the most common neoplastic lesion (22/34) observed in this study, and low-grade carcinoma was more common (seventeen cases) than high-grade carcinoma (five cases).
Papilloma, papillary urothelial neoplasm of low malignant potential (PUNLMP), and invasive carcinomas were less frequently seen.
Carcinoma in situ (CIS) was often detected associated with some papillary and invasive carcinomas.
De novo (primary) CIS was rare representing 3% of tumors of this series.
A peculiar feature of the most urothelial tumors was the presence in the tumor stroma of immune cells anatomically organized in tertiary lymphoid organs (TLOs).
Bovine papillomavirus type-2 (PV-2) E5 oncoprotein was detected by molecular and immunohistochemistry procedures.
Early protein, E2, and late protein, L1, were also detected by immunohistochemical studies.
Morphological and molecular findings show that BPV-2 infection contributes to the development of urothelial bladder carcinogenesis also in water buffaloes.
American Psychological Association (APA)
Maiolino, Paola& Özkul, Ayhan& Sepici-Dincel, Aylin& Roperto, Franco Peppino& Yücel, Gözde& Russo, Valeria…[et al.]. 2013. Bovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031121
Modern Language Association (MLA)
Maiolino, Paola…[et al.]. Bovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1031121
American Medical Association (AMA)
Maiolino, Paola& Özkul, Ayhan& Sepici-Dincel, Aylin& Roperto, Franco Peppino& Yücel, Gözde& Russo, Valeria…[et al.]. Bovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031121
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031121