Nanocarriers for Diagnosis and Targeting of Breast Cancer
Joint Authors
Jain, Nitin
Sharma, Arun
Sareen, Rashmi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Breast cancer nanotherapeutics is consistently progressing and being used to remove the various limitations of conventional method available for the diagnosis and treatment of breast cancer.
Nanoparticles provide an interdisciplinary area for research in imaging, diagnosis, and targeting of breast cancer.
With advanced physicochemical properties and better bioavailability, they show prolonged blood circulation with efficient tumor targeting.
Passive targeting mechanisms by using leaky vasculature, tumor microenvironment, or direct local application and active targeting approaches using receptor antibody, amplification in the ability of nanoparticles to target specific tumor can be achieved.
Nanoparticles are able to reduce cytotoxic effect of the active anticancer drugs by increasing cancer cell targeting in comparison to conventional formulations.
Various nanoparticles-based formulations are in the preclinical and clinical stages of development; among them, polymeric drug micelles, liposomes, dendrimer, carbon nanotubes, and nanorods are the most common.
In this review, we have discussed the role of nanoparticles with respect to oncology, by particularly focusing on the breast cancer and various nanodelivery systems used for targeting action.
American Psychological Association (APA)
Sharma, Arun& Jain, Nitin& Sareen, Rashmi. 2013. Nanocarriers for Diagnosis and Targeting of Breast Cancer. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1031148
Modern Language Association (MLA)
Sharma, Arun…[et al.]. Nanocarriers for Diagnosis and Targeting of Breast Cancer. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1031148
American Medical Association (AMA)
Sharma, Arun& Jain, Nitin& Sareen, Rashmi. Nanocarriers for Diagnosis and Targeting of Breast Cancer. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1031148
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031148