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Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study
Joint Authors
Sameiro-Faria, Maria
Bronze-da-Rocha, Elsa
Belo, Luís
Fernandes, João
Quintanilha, Alexandre
Ribeiro, Sandra
Nascimento, Henrique
Kohlova, Michaela
Amado, Leonilde
Miranda, Vasco
Rocha-Pereira, Petronila
Santos-Silva, Alice
Teixeira, Laetitia
Mendonça, Denisa
Costa, Elísio
Reis, Flávio
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
End-stage renal disease (ESRD) patients under hemodialysis (HD) have high mortality rate.
Inflammation, dyslipidemia, disturbances in erythropoiesis, iron metabolism, endothelial function, and nutritional status have been reported in these patients.
Our aim was to identify any significant association of death with these disturbances, by performing a two-year follow-up study.
Methods and Results.
A large set of data was obtained from 189 HD patients (55.0% male; 66.4 ± 13.9 years old), including hematological data, lipid profile, iron metabolism, nutritional, inflammatory, and endothelial (dys)function markers, and dialysis adequacy.
Results.
35 patients (18.5%) died along the follow-up period.
Our data showed that the type of vascular access, C-reactive protein (CRP), and triglycerides (TG) are significant predictors of death.
The risk of death was higher in patients using central venous catheter (CVC) (Hazard ratio [HR] =3.03, 95% CI = 1.49–6.13), with higher CRP levels (fourth quartile), compared with those with lower levels (first quartile) (HR = 17.3, 95% CI = 2.40–124.9).
Patients with higher TG levels (fourth quartile) presented a lower risk of death, compared with those with the lower TG levels (first quartile) (HR = 0.18, 95% CI = 0.05–0.58).
Conclusions.
The use of CVC, high CRP, and low TG values seem to be independent risk factors for mortality in HD patients.
American Psychological Association (APA)
Sameiro-Faria, Maria& Ribeiro, Sandra& Costa, Elísio& Mendonça, Denisa& Teixeira, Laetitia& Rocha-Pereira, Petronila…[et al.]. 2013. Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study. Disease Markers،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031203
Modern Language Association (MLA)
Sameiro-Faria, Maria…[et al.]. Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study. Disease Markers No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1031203
American Medical Association (AMA)
Sameiro-Faria, Maria& Ribeiro, Sandra& Costa, Elísio& Mendonça, Denisa& Teixeira, Laetitia& Rocha-Pereira, Petronila…[et al.]. Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031203
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031203