The Salivary β-HEX A% Index as an Excellent Marker of Periodontitis in Smoking Alcohol-Dependent Persons
Joint Authors
Milewski, Robert
Waszkiewicz, Napoleon
Zalewska-Szajda, Beata
Chojnowska, Sylwia
Szajda, Sławomir Dariusz
Zalewska, Anna
Konarzewska, Beata
Szulc, Agata
Wojtulewska-Supron, Aleksandra
Kępka, Alina
Knaś, Małgorzata
Ładny, Jerzy Robert
Zwierz, Krzysztof
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Severe periodontitis leading to tooth loss is found in 5–15% of most populations worldwide.
Aim.
The applicability of salivary β-hexosaminidase (β-HEX A%, percentage of β-HEX A isoenzyme to total β-HEX) and β-HEX B% (β-HEX B/β-HEX) indexes was investigated as a possible marker of periodontitis.
Methods.
Thirty three alcohol-dependent smokers (AS) and 32 healthy controls (C) were enrolled in the study.
The activity of β-HEX was measured spectrophotometrically.
Results.
β-HEX A% was significantly higher and β-HEX B% was lower in AS than in C group.
We found a significant correlation between β-HEX A% and gingival index (GI) and an inverse correlation between β-HEX A% and salivary flow (SF), in all groups.
Salivary β-HEX A% index in smoking alcoholics at 0.23 had excellent sensitivity (96%) and specificity (91%); the AUC for β-HEX A% was high (0.937).
There were no correlations between amount/duration-time of alcohol drinking/smoking and β-HEX A% or β-HEX B%.
We found significant correlations between the time period of denture wearing and GI, papilla bleeding index (PBI), and decayed missing filled teeth index (DMFT) and between GI and the amount of smoked cigarettes per day.
Conclusion.
Bad periodontal state was most likely due to the nicotine dependence.
Salivary β-HEX A% is a promising excellent marker for the diagnosis of periodontitis.
American Psychological Association (APA)
Waszkiewicz, Napoleon& Zalewska-Szajda, Beata& Chojnowska, Sylwia& Szajda, Sławomir Dariusz& Zalewska, Anna& Konarzewska, Beata…[et al.]. 2013. The Salivary β-HEX A% Index as an Excellent Marker of Periodontitis in Smoking Alcohol-Dependent Persons. Disease Markers،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031209
Modern Language Association (MLA)
Waszkiewicz, Napoleon…[et al.]. The Salivary β-HEX A% Index as an Excellent Marker of Periodontitis in Smoking Alcohol-Dependent Persons. Disease Markers No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1031209
American Medical Association (AMA)
Waszkiewicz, Napoleon& Zalewska-Szajda, Beata& Chojnowska, Sylwia& Szajda, Sławomir Dariusz& Zalewska, Anna& Konarzewska, Beata…[et al.]. The Salivary β-HEX A% Index as an Excellent Marker of Periodontitis in Smoking Alcohol-Dependent Persons. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031209
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031209