Platelets and Inflammatory Markers in Patients with Gastric Cancer
Joint Authors
Matowicka Karna, Joanna
Kemona, Halina
Polińska, Beata
Osada, Joanna
Kamocki, Zbigniew
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of the study was to assess the contribution of platelets and inflammatory markers in gastric cancer.
We studied 50 patients.
Taking into consideration the advancement of gastric cancer, patients were divided into 3 groups.
Group (E)—13 patients with early gastric cancer, group (A)—18 patients with regionally advanced cancer, and group (M)—19 patients with metastatic cancer.
The determinations were performed twice prior to surgery and after surgery.
In patients with gastric cancer, there is an increase in IL-6 and IL-23 compared with the healthy group.
The highest values of IL-6 were obtained in early cancer (more than 8-fold increase), which seems to confirm the presence of acute inflammation.
The lowest value of both of these cytokines was obtained in patients with metastatic cancer.
In all patients, regardless of tumor stage, there was an increase in the concentration of CRP.
An increase of PLT, higher proportion of the percentage of large platelets (LPLT), and increased mean platelet volume (MPV) were observed in the process of disease development.
A positive correlation between MPV and LPLT and the accompanying decrease in the concentration of proinflammatory cytokines indicates the presence of an existing relationship between the platelet morphological parameters and the inflammation process in the development of gastric cancer.
American Psychological Association (APA)
Matowicka Karna, Joanna& Kamocki, Zbigniew& Polińska, Beata& Osada, Joanna& Kemona, Halina. 2013. Platelets and Inflammatory Markers in Patients with Gastric Cancer. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031277
Modern Language Association (MLA)
Matowicka Karna, Joanna…[et al.]. Platelets and Inflammatory Markers in Patients with Gastric Cancer. Journal of Immunology Research No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1031277
American Medical Association (AMA)
Matowicka Karna, Joanna& Kamocki, Zbigniew& Polińska, Beata& Osada, Joanna& Kemona, Halina. Platelets and Inflammatory Markers in Patients with Gastric Cancer. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031277