Latent Abnormal Pathology Affects Long-Term Graft Function in Elder Living Renal Allograft Recipients
Joint Authors
Du, Yu
Guo, Hongbo
Zhang, Lei
Tian, Ye
Xie, Zelin
Tang, Yawang
Zhang, Mengmeng
Ma, Linlin
Sun, Wen
Bi, Rumei
Lin, Jun
Zhu, Xi
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
This study evaluated the long-term effects and clinical significance of latent abnormal pathology on elder living donor kidney graft function after renal transplantation in China.
Methods.
One-hundred and thirty-eight living donor renal transplantations have been carried out at our hospital in recent years.
Of these, 72 Time-Zero biopsies were performed and used in this analysis.
Clinical data were retrospectively measured at 3, 6, 12, and 24 months after renal transplants.
Relationships and effects from biopsy results taken from implanted donor kidney grafts were analyzed.
Results.
Time-Zero biopsy pathology results from donor kidneys showed that 48.61% of donor kidneys had latent abnormal changes; arterial lesions of donor kidneys had significant effects on the renal function of grafts after 2 years' transplantation; correlations between donor age and arterial lesions were significant; and Time-Zero biopsy pathology results could help predict the long-term function of a renal graft.
Conclusions.
Existing latent pathological changes of an elder living donor kidney before transplantation could affect long-term renal function.
Whether a senior donor is used should be very carefully considered.
American Psychological Association (APA)
Ma, Linlin& Zhang, Lei& Du, Yu& Xie, Zelin& Tang, Yawang& Lin, Jun…[et al.]. 2013. Latent Abnormal Pathology Affects Long-Term Graft Function in Elder Living Renal Allograft Recipients. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1031285
Modern Language Association (MLA)
Ma, Linlin…[et al.]. Latent Abnormal Pathology Affects Long-Term Graft Function in Elder Living Renal Allograft Recipients. Journal of Immunology Research No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1031285
American Medical Association (AMA)
Ma, Linlin& Zhang, Lei& Du, Yu& Xie, Zelin& Tang, Yawang& Lin, Jun…[et al.]. Latent Abnormal Pathology Affects Long-Term Graft Function in Elder Living Renal Allograft Recipients. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1031285
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031285