Porous Ti6Al4V Scaffold Directly Fabricated by Sintering: Preparation and In Vivo Experiment
Joint Authors
Zheng, Guoquan
Zhang, Xuesong
Zheng, Guoquan
Wang, Jiaqi
Zhang, Yonggang
Li, Zhongli
Wang, Yan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The interface between the implant and host bone plays a key role in maintaining primary and long-term stability of the implants.
Surface modification of implant can enhance bone ingrowth and increase bone formation to create firm osseointegration between the implant and host bone and reduce the risk of implant losing.
This paper mainly focuses on the fabricating of 3-dimensiona interconnected porous titanium by sintering of Ti6Al4V powders, which could be processed to the surface of the implant shaft and was integrated with bone morphogenetic proteins (BMPs).
The structure and mechanical property of porous Ti6Al4V was observed and tested.
Implant shaft with surface of porous titanium was implanted into the femoral medullary cavity of dog after combining with BMPs.
The results showed that the structure and elastic modulus of 3D interconnected porous titanium was similar to cancellous bone; porous titanium combined with BMP was found to have large amount of fibrous tissue with fibroblastic cells; bone formation was significantly greater in 6 weeks postoperatively than in 3 weeks after operation.
Porous titanium fabricated by powders sintering and combined with BMPs could induce tissue formation and increase bone formation to create firm osseointegration between the implant and host bone.
American Psychological Association (APA)
Zhang, Xuesong& Zheng, Guoquan& Wang, Jiaqi& Zhang, Yonggang& Zheng, Guoquan& Li, Zhongli…[et al.]. 2013. Porous Ti6Al4V Scaffold Directly Fabricated by Sintering: Preparation and In Vivo Experiment. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031318
Modern Language Association (MLA)
Zhang, Xuesong…[et al.]. Porous Ti6Al4V Scaffold Directly Fabricated by Sintering: Preparation and In Vivo Experiment. Journal of Nanomaterials No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1031318
American Medical Association (AMA)
Zhang, Xuesong& Zheng, Guoquan& Wang, Jiaqi& Zhang, Yonggang& Zheng, Guoquan& Li, Zhongli…[et al.]. Porous Ti6Al4V Scaffold Directly Fabricated by Sintering: Preparation and In Vivo Experiment. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1031318
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031318