Fabrication of Gold Nanochains with Octreotide Acetate Template
Joint Authors
Gao, Faming
Zhou, Jing
Fu, Zhanzhao
Gao, Dawei
Li, Na
Zhao, Xiaoning
Liu, Yanping
Wang, Zi
Wang, Guangxia
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We described a facile method for assembly gold nanochains by using octreotide acetate as template in aqueous environment.
In acidic solution, octreotide acetate was conferred positive charges and its structure changed to chain-like.
The monodisperse negative gold nanoparticles were bound to the surface of octreotide acetate template by electrostatic attraction and the interaction of gold nanoparticles with amino acid residues (tryptophan and lysine).
The fabricated gold nanostructure presented chain-like observed by transmission electron microscopy.
The cytotoxicity of gold nanochains was examined by tetrazolium dye-based microtitration (MTT) assay, which demonstrated significantly less toxicity than that of octreotide acetate alone.
The MTT assay also reflected the combinative action between the gold nanoparticles with octreotide acetate.
Our work lays the groundwork for developing octreotide acetate-templated nanomaterials that can be used as a building block for the creation of nanomaterials.
Meanwhile, the harmfulless gold nanochains have great application prospects in the biomedical filed.
American Psychological Association (APA)
Zhou, Jing& Fu, Zhanzhao& Gao, Dawei& Gao, Faming& Li, Na& Zhao, Xiaoning…[et al.]. 2013. Fabrication of Gold Nanochains with Octreotide Acetate Template. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031343
Modern Language Association (MLA)
Zhou, Jing…[et al.]. Fabrication of Gold Nanochains with Octreotide Acetate Template. Journal of Nanomaterials No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1031343
American Medical Association (AMA)
Zhou, Jing& Fu, Zhanzhao& Gao, Dawei& Gao, Faming& Li, Na& Zhao, Xiaoning…[et al.]. Fabrication of Gold Nanochains with Octreotide Acetate Template. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031343
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031343