Fabrication of Pamidronic Acid-Immobilized TiO2Hydroxyapatite Composite Nanofiber Mats for Biomedical Applications
Joint Authors
Haider, Adnan
Shin, Yong-Suk
Borah, Jyoti S.
Huh, Man-Woo
Kang, Inn-Kyu
Kim, Sukyoung
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
TiO2/hydroxyapatite (TiO2/HA) composite nanofiber mats were fabricated using an electrospinning technique.
Subsequently, pamidronic acid (PDA) was immobilized on the surface of the TiO2/HA nanofiber mat to improve osseointegration.
X-ray photoelectron microscopy and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the PDA-immobilized TiO2/HA composite nanofiber mat (TiO2/HA-P).
The potential of TiO2/HA-P as a bone scaffold was assessed by examining the cell adhesion and proliferation of osteoblasts and osteoclasts.
The adhesion and proliferation of osteoblasts on the TiO2/HA-P composite nanofiber mat were slightly higher than those on the TiO2/HA composite nanofiber mat, whereas the viability of osteoclasts on the TiO2/HA-P nanofiber mat was significantly suppressed.
These results suggest that the TiO2/HA-P nanofiber mat has the potential for use as a therapeutic bone implant.
American Psychological Association (APA)
Shin, Yong-Suk& Borah, Jyoti S.& Haider, Adnan& Kim, Sukyoung& Huh, Man-Woo& Kang, Inn-Kyu. 2013. Fabrication of Pamidronic Acid-Immobilized TiO2Hydroxyapatite Composite Nanofiber Mats for Biomedical Applications. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031372
Modern Language Association (MLA)
Shin, Yong-Suk…[et al.]. Fabrication of Pamidronic Acid-Immobilized TiO2Hydroxyapatite Composite Nanofiber Mats for Biomedical Applications. Journal of Nanomaterials No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1031372
American Medical Association (AMA)
Shin, Yong-Suk& Borah, Jyoti S.& Haider, Adnan& Kim, Sukyoung& Huh, Man-Woo& Kang, Inn-Kyu. Fabrication of Pamidronic Acid-Immobilized TiO2Hydroxyapatite Composite Nanofiber Mats for Biomedical Applications. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031372