A Review of the Effect of Processing Variables on the Fabrication of Electrospun Nanofibers for Drug Delivery Applications
Joint Authors
du Toit, Lisa C.
Pillay, Viness
Dott, Clare
Tyagi, Charu
Tomar, Lomas
Kumar, Pradeep
Ndesendo, Valence M. K.
Choonara, Yahya E.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-13
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
Electrospinning is a fast emerging technique for producing ultrafine fibers by utilizing electrostatic repulsive forces.
The technique has gathered much attention due to the emergence of nanotechnology that sparked worldwide research interest in nanomaterials for their preparation and application in biomedicine and drug delivery.
Electrospinning is a simple, adaptable, cost-effective, and versatile technique for producing nanofibers.
For effective and efficient use of the technique,several processing parameters need to be optimized for fabricating polymeric nanofibers.
The nanofiber morphology, size, porosity, surface area, and topography can be refined by varying these parameters.
Such flexibility and diversity in nanofiber fabrication by electrospinning has broadened the horizons for widespread application of nanofibers in the areas of drug and gene delivery, wound dressing, and tissue engineering.
Drug-loaded electrospun nanofibers have been used in implants, transdermal systems, wound dressings, and as devices for aiding the prevention of postsurgical abdominal adhesions and infection.
They show great promise for use in drug delivery provided that one can confidently control the processing variables during fabrication.
This paper provides a concise incursion into the application of electrospun nanofibers in drug delivery and cites pertinent processing parameters that may influence the performance of the nanofibers when applied to drug delivery.
American Psychological Association (APA)
Pillay, Viness& Dott, Clare& Choonara, Yahya E.& Tyagi, Charu& Tomar, Lomas& Kumar, Pradeep…[et al.]. 2013. A Review of the Effect of Processing Variables on the Fabrication of Electrospun Nanofibers for Drug Delivery Applications. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1031556
Modern Language Association (MLA)
Pillay, Viness…[et al.]. A Review of the Effect of Processing Variables on the Fabrication of Electrospun Nanofibers for Drug Delivery Applications. Journal of Nanomaterials No. 2013 (2013), pp.1-22.
https://search.emarefa.net/detail/BIM-1031556
American Medical Association (AMA)
Pillay, Viness& Dott, Clare& Choonara, Yahya E.& Tyagi, Charu& Tomar, Lomas& Kumar, Pradeep…[et al.]. A Review of the Effect of Processing Variables on the Fabrication of Electrospun Nanofibers for Drug Delivery Applications. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1031556
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031556