Cytotoxic Effect of Nanocrystalline MgFe2O4 Particles for Cancer Cure
Joint Authors
Hashim, M.
Alitheen, Noorjahan Banu Mohamed
Bahmanrokh, G.
Kanagesan, S.
Ismail, I.
Subramani, Tamilselvan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Nanocrystalline magnesium ferrites (MgFe2O4) were produced with an average grain size of about 20 nm.
Their structural, morphological, and magnetic characterizations were studied.
The cytotoxic effects of MgFe2O4 nanoparticles in various concentrations (25, 50, 100, 200, 400, and 800 μg/mL) against MCF-7 human breast cancer cells were analyzed.
MTT assay findings suggest the increased accumulation of apoptotic bodies with the increasing concentration of MgFe2O4 nanoparticles in a dose-dependent manner.
Flow cytometry analysis shows that MgFe2O4 nanoparticles in 800 μg/mL concentration are more cytotoxic compared to vehicle-treated MCF-7 cells and suggests their potential utility as a drug carrier in the treatment of cancer.
American Psychological Association (APA)
Kanagesan, S.& Hashim, M.& Subramani, Tamilselvan& Alitheen, Noorjahan Banu Mohamed& Ismail, I.& Bahmanrokh, G.. 2013. Cytotoxic Effect of Nanocrystalline MgFe2O4 Particles for Cancer Cure. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031603
Modern Language Association (MLA)
Kanagesan, S.…[et al.]. Cytotoxic Effect of Nanocrystalline MgFe2O4 Particles for Cancer Cure. Journal of Nanomaterials No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1031603
American Medical Association (AMA)
Kanagesan, S.& Hashim, M.& Subramani, Tamilselvan& Alitheen, Noorjahan Banu Mohamed& Ismail, I.& Bahmanrokh, G.. Cytotoxic Effect of Nanocrystalline MgFe2O4 Particles for Cancer Cure. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031603