Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium PhosphateCollagen Scaffolds
Joint Authors
Yan, Wei
Zhang, Xuehui
Xu, Mingming
Liu, Xinggang
Zhang, Feng
Meng, Song
Dai, Xiaohan
Duan, Aizhu
Liang, Xu-Deng
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Nano-β-tricalcium phosphate/collagen (n-β-TCP/Col) is considered with good osteoconductivity.
However, the therapeutic effectiveness of n-β-TCP/Col scaffolds in combination with autologous bone marrow stromal cells (BMSCs) remains to be elucidated for the repair of critical-sized bone defects.
In this study, we found that n-β-TCP/Col scaffolds exhibited high biocompatibility in vitro.
The introduction of BMSCs expanded in vitro to the scaffolds dramatically enhanced their efficiency to restore critical-sized bone defects, especially during the initial stage after implantation.
Collectively, these results suggest that autologous BMSCs in n-β-TCP/Col scaffolds have the potential to be applied in bone tissue engineering.
American Psychological Association (APA)
Zhang, Xuehui& Xu, Mingming& Liu, Xinggang& Zhang, Feng& Yan, Wei& Meng, Song…[et al.]. 2013. Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium PhosphateCollagen Scaffolds. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031617
Modern Language Association (MLA)
Zhang, Xuehui…[et al.]. Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium PhosphateCollagen Scaffolds. Journal of Nanomaterials No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1031617
American Medical Association (AMA)
Zhang, Xuehui& Xu, Mingming& Liu, Xinggang& Zhang, Feng& Yan, Wei& Meng, Song…[et al.]. Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium PhosphateCollagen Scaffolds. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031617
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1031617