Speciation Studies of Diorganotin(IV)‎ Complexes with 3,3-Bis(1-methylimidazol-2-yl)‎propionate—Displacement Reaction by DNA Constituents

Abstract EN

The interaction of 3,3-bis(1-methylimidazol-2-yl)propionate (BIMP) with dimethyltin(IV) dichloride (DMT), dibutyltin(IV) dichloride (DBT), and diphenyltin(IV) dichloride (DPT) is investigated at 25°C and 0.1 M ionic strength in water for dimethyltin(IV), and in a 50% dioxane-water mixture for dibutyltin(IV) and diphenyltin(IV).

The stepwise formation constants of the 1 : 1 and 1 : 2 complexes formed in solution are calculated from potentiometric measurements using the nonlinear least-square program MINIQUAD-75.

The concentration distribution of the various complex species is evaluated as a function of pH.

Displacement reactions of the coordinated 3,3-bis(1-methylimidazol-2-yl)propionate by inosine and inosine-5′-monophosphate are investigated from calculations based upon equilibrium properties.