Antimelanoma and Antityrosinase from Alpinia galangal Constituents

Joint Authors

Liu, Po-Len
Hseu, You Cheng
Chen, Yen-Ting
Lo, Chih-Yu
Wang, Hui-Min
Lin, Li-Ching
Wen, Zhi-Hong

Source

The Scientific World Journal

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-08-21

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Medicine
Information Technology and Computer Science

Abstract EN

Two compounds, 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one (BHPHTO) and bisdemethoxycurcumin (BDMC) they have been isolated from the rhizomes of Alpinia galangal, and the structures of both pure constituents were determined using spectroscopic analyses.

The study examined the bioeffectivenesses of the two compounds on the human melanoma A2058 and showed that significantly inhibited the proliferation of melanoma cells in the cell viability assay.

This research was also taken on the tests to B16-F10 cell line and showed minor inhibitory consequences of cellular tyrosinase activities and melanin contents.

Our results revealed the anticancer effects of A.

galangal compounds, and therefore, the target compounds could be potentially applied in the therapeutic application and the food industry.

American Psychological Association (APA)

Lo, Chih-Yu& Liu, Po-Len& Lin, Li-Ching& Chen, Yen-Ting& Hseu, You Cheng& Wen, Zhi-Hong…[et al.]. 2013. Antimelanoma and Antityrosinase from Alpinia galangal Constituents. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1032629

Modern Language Association (MLA)

Lo, Chih-Yu…[et al.]. Antimelanoma and Antityrosinase from Alpinia galangal Constituents. The Scientific World Journal No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1032629

American Medical Association (AMA)

Lo, Chih-Yu& Liu, Po-Len& Lin, Li-Ching& Chen, Yen-Ting& Hseu, You Cheng& Wen, Zhi-Hong…[et al.]. Antimelanoma and Antityrosinase from Alpinia galangal Constituents. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1032629

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1032629