Children with Congenital Hypothyroidism Have Similar Neuroradiological Abnormal Findings as Healthy Ones
Joint Authors
Rachmiel, Marianna
Blaser, Susanne
Widjaja, Elysa
Rovet, Joanne
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Objective.
To assess the neuroradiological findings of children with congenital hypothyroidism (CHT) compared to healthy controls (HC).
Patients and Methods.
Thirty children with CHT, mean age 12.5 ± 1.6 years, 14 (44.8%) males, were compared with 38 HC mean age 11.7 ± 1.7 years, 16 (45.7%) males.
Clinical data were collected from medical charts and questionnaires seeking information on family history, birth and perinatal period events, medications, and overall health history.
Neurocognitive function was assessed for global intelligence, visual and verbal memory, and executive functioning using standardized tests.
Neuroimaging was performed using 1.5 T magnetic resonance imaging and assessed by two pediatric radiologists.
Results.
Children with CHT had a similar proportion of incidental findings as did the children in the HC group, at 43.3% and 39.5%, respectively, P=0.69.
Abnormalities of the sellar region were reported in 13.3% of CHT group and 7.9% of HC group, P=0.46.
Other incidental findings included cerebellar ectopia, choroidal fissure and pineal cysts, and multiple increased signal intensity foci.
Neuroradiological findings were not associated with clinical and neurocognitive abnormalities.
Conclusion.
Neuroimaging of children with CHT demonstrated a similar incidence of structural abnormalities as in the healthy population.
There is no association between those findings and neurocognitive function.
American Psychological Association (APA)
Rachmiel, Marianna& Blaser, Susanne& Widjaja, Elysa& Rovet, Joanne. 2013. Children with Congenital Hypothyroidism Have Similar Neuroradiological Abnormal Findings as Healthy Ones. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1032641
Modern Language Association (MLA)
Rachmiel, Marianna…[et al.]. Children with Congenital Hypothyroidism Have Similar Neuroradiological Abnormal Findings as Healthy Ones. The Scientific World Journal No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-1032641
American Medical Association (AMA)
Rachmiel, Marianna& Blaser, Susanne& Widjaja, Elysa& Rovet, Joanne. Children with Congenital Hypothyroidism Have Similar Neuroradiological Abnormal Findings as Healthy Ones. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1032641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1032641