Antimicrobial, Antiparasitic, Anti-Inflammatory, and Cytotoxic Activities of Lopezia racemosa
Joint Authors
Juárez, Zaida N.
Cruz Paredes, Carla
Bolívar Balbás, Paulina
Gómez-Velasco, Anaximandro
Sánchez Arreola, Eugenio
Bach, Horacio
Hernández, Luis R.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The present study investigates the potential benefits of the Mexican medicinal plant Lopezia racemosa (Onagraceae).
Extracts and fractions from aerial parts of this plant were assessed to determine their antibacterial, antifungal, antiparasitic, anti-inflammatory and cytotoxic activities in vitro.
Aerial parts of the plant were extracted with various solvents and fractionated accordingly.
Extracts and fractions were tested against a panel of nine bacterial and four fungal species.
The antiparasitic activity was tested against Leishmania donovani, whereas the anti-inflammatory activity of the compounds was determined by measuring the secretion of interleukin-6 from human-derived macrophages.
The same macrophage cell line was used to investigate the cytotoxicity of the compounds.
Various extracts and fractions showed antibacterial, antifungal, antiparasitic, and anti-inflammatory activities.
The hexanic fraction HF 11-14b was the most interesting fraction with antimicrobial, and anti-inflammatory activities.
The benefit of L.
racemosa as a traditional medicinal plant was confirmed as shown by its antibacterial, antifungal and anti-inflammatory activities.
To the best of our knowledge, this is the first study reporting the biological activities of L.
racemosa, including antiparasitic and anti-inflammatory activities.
American Psychological Association (APA)
Cruz Paredes, Carla& Bolívar Balbás, Paulina& Gómez-Velasco, Anaximandro& Juárez, Zaida N.& Sánchez Arreola, Eugenio& Hernández, Luis R.…[et al.]. 2013. Antimicrobial, Antiparasitic, Anti-Inflammatory, and Cytotoxic Activities of Lopezia racemosa. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1032685
Modern Language Association (MLA)
Cruz Paredes, Carla…[et al.]. Antimicrobial, Antiparasitic, Anti-Inflammatory, and Cytotoxic Activities of Lopezia racemosa. The Scientific World Journal No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1032685
American Medical Association (AMA)
Cruz Paredes, Carla& Bolívar Balbás, Paulina& Gómez-Velasco, Anaximandro& Juárez, Zaida N.& Sánchez Arreola, Eugenio& Hernández, Luis R.…[et al.]. Antimicrobial, Antiparasitic, Anti-Inflammatory, and Cytotoxic Activities of Lopezia racemosa. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1032685
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1032685