NP-59 SPECTCT Imaging in Stage 1 Hypertensive and Atypical Primary Aldosteronism: A 5-Year Retrospective Analysis of Clinicolaboratory and Imaging Features
Joint Authors
Chiu, Jainn-Shiun
Wang, Yuh-Feng
Chen, Yi-Chun
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Objective.
We retrospectively analyzed all primary aldosteronism (PA) patients undergoing NP-59 SPECT/CT imaging with regard to their clinicolaboratory and imaging features, investigation, and outcomes.
Material and Methods.
11 PA patients who presented to our hospital for NP-59 SPECT/CT imaging between April 2007 and March 2012 and managed here were analyzed.
Results.
Among 11 PA patients, eight (73%) had stage 1 hypertension, three (27%) stage 2 hypertension, four (36%) normal plasma aldosterone concentration, nine (82%) nonsuppressed plasma renin activity (PRA), six (55%) normal aldosterone-renin-ratio (ARR), eight (73%) serum potassium ≧3 mEq/L, seven (64%) subclinical presentation, seven (64%) negative confirmatory testing, and four (36%) inconclusive results on CT scan and seven (64%) on planar NP-59 scan.
All 11 (100%) patients had positive results on NP-59 SPECT/CT scan.
Two (18%) met typical triad and nine (82%) atypical triad.
Among nine atypical PA patients, three (33%) had clinical presentation, six (67%) subclinical presentation, six (67%) negative confirmatory testing, and four (44%) inconclusive results on CT scan and six (67%) on planar NP-59 scan.
All patients had improved outcomes.
Significant differences between typical and atypical PA existed in PRA and ARR.
Conclusions.
NP-59 SPECT/CT may provide diagnostic potential in stage 1 hypertensive and atypical PA.
American Psychological Association (APA)
Chen, Yi-Chun& Chiu, Jainn-Shiun& Wang, Yuh-Feng. 2013. NP-59 SPECTCT Imaging in Stage 1 Hypertensive and Atypical Primary Aldosteronism: A 5-Year Retrospective Analysis of Clinicolaboratory and Imaging Features. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1032785
Modern Language Association (MLA)
Chen, Yi-Chun…[et al.]. NP-59 SPECTCT Imaging in Stage 1 Hypertensive and Atypical Primary Aldosteronism: A 5-Year Retrospective Analysis of Clinicolaboratory and Imaging Features. The Scientific World Journal No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1032785
American Medical Association (AMA)
Chen, Yi-Chun& Chiu, Jainn-Shiun& Wang, Yuh-Feng. NP-59 SPECTCT Imaging in Stage 1 Hypertensive and Atypical Primary Aldosteronism: A 5-Year Retrospective Analysis of Clinicolaboratory and Imaging Features. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1032785
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1032785