Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy
Joint Authors
Veselka, J.
Krejci, Jan
Gregor, Pavel
Zemanek, David
Vyskocilova, Klaudia
Curila, Karol
Stepanova, Radka
Novak, Miroslav
Groch, Ladislav
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Introduction.
Nonpharmacological treatment of patients with hypertrophic obstructive cardiomyopathy (HOCM) comprises surgical myectomy (SME), alcohol septal ablation (ASA), and dual-chamber (DDD) pacing.
The aim of the study was to compare the long-term effect of DDD pacing and ASA in symptomatic HOCM patients.
Patients and Methods.
We evaluated retrospective data from three cardiocenters; there were 24 patients treated with DDD pacing included and 52 treated with ASA followed for 101 ± 49 and 87 ± 23 months, respectively.
Results.
In the group treated with DDD pacing, the left ventricle outflow tract gradient (LVOTG) decreased from 82 ± 44 mmHg to 21 ± 21 mmHg, and NYHA class improved from 2.7 ± 0.5 to 2.1 ± 0.6 (both P<0.001).
In the ASA-treated group, a decline in LVOTG from 73 ± 38 mmHg to 24 ± 26 mmHg and reduction in NYHA class from 2.8 ± 0.5 to 1.7 ± 0.8 were observed (both P<0.001).
The LVOTG change was similar in both groups (P=0.264), and symptoms were more affected by ASA (P=0.001).
Conclusion.
ASA and DDD pacing were similarly effective in reducing LVOTG.
The symptoms improvement was more expressed in patients treated with ASA.
American Psychological Association (APA)
Krejci, Jan& Gregor, Pavel& Zemanek, David& Vyskocilova, Klaudia& Curila, Karol& Stepanova, Radka…[et al.]. 2013. Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033139
Modern Language Association (MLA)
Krejci, Jan…[et al.]. Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy. The Scientific World Journal No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1033139
American Medical Association (AMA)
Krejci, Jan& Gregor, Pavel& Zemanek, David& Vyskocilova, Klaudia& Curila, Karol& Stepanova, Radka…[et al.]. Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033139
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1033139