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Alternative Splicing for Diseases, Cancers, Drugs, and Databases
Joint Authors
Chang, Hsueh-Wei
Tang, Jen-Yang
Wang, Chun-Lin
Chen, Chien-Chi
Huang, Hurng-Wern
Lee, Jin-Ching
Hou, Ming-Feng
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Alternative splicing is a major diversification mechanism in the human transcriptome and proteome.
Several diseases, including cancers, have been associated with dysregulation of alternative splicing.
Thus, correcting alternative splicing may restore normal cell physiology in patients with these diseases.
This paper summarizes several alternative splicing-related diseases, including cancers and their target genes.
Since new cancer drugs often target spliceosomes, several clinical drugs and natural products or their synthesized derivatives were analyzed to determine their effects on alternative splicing.
Other agents known to have modulating effects on alternative splicing during therapeutic treatment of cancer are also discussed.
Several commonly used bioinformatics resources are also summarized.
American Psychological Association (APA)
Tang, Jen-Yang& Lee, Jin-Ching& Hou, Ming-Feng& Wang, Chun-Lin& Chen, Chien-Chi& Huang, Hurng-Wern…[et al.]. 2013. Alternative Splicing for Diseases, Cancers, Drugs, and Databases. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1033211
Modern Language Association (MLA)
Tang, Jen-Yang…[et al.]. Alternative Splicing for Diseases, Cancers, Drugs, and Databases. The Scientific World Journal No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1033211
American Medical Association (AMA)
Tang, Jen-Yang& Lee, Jin-Ching& Hou, Ming-Feng& Wang, Chun-Lin& Chen, Chien-Chi& Huang, Hurng-Wern…[et al.]. Alternative Splicing for Diseases, Cancers, Drugs, and Databases. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1033211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1033211