Hepatitis C Virus Infection: Looking for Interferon Free Regimens

Abstract EN

Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection.

Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research.

Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon.

The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations.