Pharmacological Effects of Active Compounds on Neurodegenerative Disease with Gastrodia and Uncaria Decoction, a Commonly Used Poststroke Decoction
Joint Authors
Chik, Stanley C. C.
Or, Terry C. T.
Luo, D.
Yang, Cindy L. H.
Lau, Allan S. Y.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-14
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Neurodegenerative diseases refer to the selective loss of neuronal systems in patients.
The diseases cause high morbidity and mortality to approximately 22 million people worldwide and the number is expected to be tripled by 2050.
Up to now, there is no effective prevention and treatment for the neurodegenerative diseases.
Although some of the clinical therapies target at slowing down the progression of symptoms of the diseases, the general effectiveness of the drugs has been far from satisfactory.
Traditional Chinese medicine becomes popular alternative remedies as it has been practiced clinically for more than thousands of years in China.
As neurodegenerative diseases are mediated through different pathways, herbal decoction with multiple herbs is used as an effective therapeutic approach to work on multiple targets.
Gastrodia and Uncaria Decoction, a popular TCM decoction, has been used to treat stroke in China.
The decoction contains compounds including alkaloids, flavonoids, iridoids, carotenoids, and natural phenols, which have been found to possess anti-inflammatory, antioxidative, and antiapoptotic effects.
In this review, we will summarize the recent publications of the pharmacological effects of these five groups of compounds.
Understanding the mechanisms of action of these compounds may provide new treatment opportunities for the patients with neurodegenerative diseases.
American Psychological Association (APA)
Chik, Stanley C. C.& Or, Terry C. T.& Luo, D.& Yang, Cindy L. H.& Lau, Allan S. Y.. 2013. Pharmacological Effects of Active Compounds on Neurodegenerative Disease with Gastrodia and Uncaria Decoction, a Commonly Used Poststroke Decoction. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1033415
Modern Language Association (MLA)
Chik, Stanley C. C.…[et al.]. Pharmacological Effects of Active Compounds on Neurodegenerative Disease with Gastrodia and Uncaria Decoction, a Commonly Used Poststroke Decoction. The Scientific World Journal No. 2013 (2013), pp.1-22.
https://search.emarefa.net/detail/BIM-1033415
American Medical Association (AMA)
Chik, Stanley C. C.& Or, Terry C. T.& Luo, D.& Yang, Cindy L. H.& Lau, Allan S. Y.. Pharmacological Effects of Active Compounds on Neurodegenerative Disease with Gastrodia and Uncaria Decoction, a Commonly Used Poststroke Decoction. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1033415
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1033415